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Gastro-oesophageal reflux disease — UKMLA Revision Notes

Gastro-oesophageal reflux disease is an important clinical condition in Gastroenterology that is tested in the UKMLA Applied Knowledge Test (AKT). Medical students and doctors preparing for the UKMLA or PLAB 1 must understand the pathophysiology, clinical presentation, investigations, and evidence-based management of Gastro-oesophageal reflux disease as outlined in current NICE guidelines.

Key Facts

  • Gastro-oesophageal reflux disease is a key condition on the GMC UKMLA Content Map
  • Commonly tested in the Gastroenterology section of the UKMLA Applied Knowledge Test
  • Understand the pathophysiology, clinical features, investigations, and management
  • NICE guidelines provide the evidence base for management decisions
  • Consider differential diagnoses and red flag symptoms in clinical scenarios

Investigations

  • FBC, U&E, LFTs, CRP
  • Endoscopy (OGD/colonoscopy)
  • CT abdomen/pelvis
  • Stool cultures
  • Faecal calprotectin
  • Abdominal USS

Management

  • Dietary modification
  • PPI/H2 antagonist as indicated
  • Treat underlying cause (H. pylori eradication, IBD therapy)
  • Nutritional support
  • Gastroenterology follow-up
  • Endoscopic surveillance if required

Practice 4+ Gastro-oesophageal reflux disease Questions

Test your knowledge with SBA questions on Gastro-oesophageal reflux disease and all 430 UKMLA Content Map conditions. Instant feedback, NICE guideline explanations, and spaced repetition included.