Psychiatry1 UKMLA question
First episode psychosis — UKMLA Revision Notes
First episode psychosis is an important clinical condition in Psychiatry that is tested in the UKMLA Applied Knowledge Test (AKT). Medical students and doctors preparing for the UKMLA or PLAB 1 must understand the pathophysiology, clinical presentation, investigations, and evidence-based management of First episode psychosis as outlined in current NICE guidelines.
Key Facts
- First episode psychosis is a key condition on the GMC UKMLA Content Map
- Commonly tested in the Psychiatry section of the UKMLA Applied Knowledge Test
- Understand the pathophysiology, clinical features, investigations, and management
- NICE guidelines provide the evidence base for management decisions
- Consider differential diagnoses and red flag symptoms in clinical scenarios
Investigations
- MSE (mental state exam)
- Collateral history
- Cognitive assessment (MMSE/MoCA)
- TFTs, FBC, U&E
- Urine drug screen
- CT/MRI head (if indicated)
Management
- Psychoeducation and support
- Psychological therapy (CBT, DBT)
- Pharmacotherapy as indicated
- Crisis plan and safety netting
- Psychiatry outpatient follow-up
- Social support and community resources